|Other Names||Actin, gamma-enteric smooth muscle, Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin, ACTG2, ACTA3, ACTL3, ACTSG|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13537b was selected from the C-term region of ACTG2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||ACTA3, ACTL3, ACTSG|
|Function||Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.|
|Cellular Location||Cytoplasm, cytoskeleton.|
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Actins are highly conserved proteins that are involved invarious types of cell motility, and maintenance of thecytoskeleton. In vertebrates, three main groups of actin isoforms,alpha, beta and gamma have been identified. The alpha actins arefound in muscle tissues and are a major constituent of thecontractile apparatus. The beta and gamma actins co-exist in mostcell types as components of the cytoskeleton, and as mediators ofinternal cell motility. Actin, gamma 2, encoded by this gene, is asmooth muscle actin found in enteric tissues.
Sun, Q., et al. J. Biol. Chem. 284(47):32582-32590(2009)Laasanen, J., et al. Fetal. Diagn. Ther. 23(1):36-40(2008)Goldberg, M.T., et al. J. Invest. Dermatol. 127(11):2645-2655(2007)Yonemoto, S., et al. Clin. Exp. Nephrol. 10(3):186-192(2006)Chang, K.W., et al. Hepatol. Res. 36(1):33-39(2006)
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