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CHRNA1 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P02708
Clone Names 100427287
Peptide ID 100427287
Additional Information
Gene ID 1134
Other Names Acetylcholine receptor subunit alpha, CHRNA1, ACHRA, CHNRA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13550b was selected from the C-term region of CHRNA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus
Research Areas
Citations (0)

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The muscle acetylcholine receptor consiststs of 5 subunitsof 4 different types: 2 alpha isoforms and 1 each of beta, gamma,and delta subunits.2 This gene encodes an alpha subunit that playsa role in acetlycholine binding/channel gating. Alternativelyspliced transcript variants encoding different isoforms have beenidentified.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Ehringer, M.A., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (2), 600-609 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 80.00
Cat# BP13550b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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