|Other Names||Carbonic anhydrase-related protein 10, Carbonic anhydrase-related protein X, CA-RP X, CARP X, Cerebral protein 15, CA10|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13563c was selected from the Center region of CA10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Does not have a catalytic activity.|
|Tissue Location||Strong expression in brain and central nervous system.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that belongs to the carbonicanhydrase family of zinc metalloenzymes, which catalyze thereversible hydration of carbon dioxide in various biologicalprocesses. The protein encoded by this gene is an acatalytic memberof the alpha-carbonic anhydrase subgroup, and it is thought to playa role in the central nervous system, especially in braindevelopment. Multiple transcript variants encoding the same proteinhave been found for this gene.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Trynka, G., et al. Gut 58(8):1078-1083(2009)Mori, S., et al. J. Bone Miner. Metab. 27(2):213-216(2009)Sonuga-Barke, E.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :Olsen, J.V., et al. Cell 127(3):635-648(2006)
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