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USP40 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NVE5 |
|---|---|
| Clone Names | 100405139 |
| Gene ID | 55230 |
|---|---|
| Other Names | Ubiquitin carboxyl-terminal hydrolase 40, Deubiquitinating enzyme 40, Ubiquitin thioesterase 40, Ubiquitin-specific-processing protease 40, USP40 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13572a was selected from the N-term region of USP40. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | USP40 |
|---|---|
| Function | May be catalytically inactive. |
| Tissue Location | Broadly expressed.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Modification of cellular proteins by ubiquitin is anessential regulatory mechanism controlled by the coordinated actionof multiple ubiquitin-conjugating and deubiquitinating enzymes.USP40 belongs to a large family of cysteine proteases that functionas deubiquitinating enzymes (Quesada et al., 2004 [PubMed14715245]).
References
Wu, Y.R., et al. Clin. Chim. Acta 411 (13-14), 955-958 (2010) :Li, Y., et al. Hum. Mutat. 27(10):1017-1023(2006)Hillier, L.W., et al. Nature 434(7034):724-731(2005)Quesada, V., et al. Biochem. Biophys. Res. Commun. 314(1):54-62(2004)Puente, X.S., et al. Nat. Rev. Genet. 4(7):544-558(2003)
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