|Other Names||Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32, DEAD/H box 32, DEAD/H helicase-like protein 1, DHLP1, DEAH box protein 32, HuDDX32, DHX32, DDX32|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13575c was selected from the Center region of DHX32. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Nucleus. Mitochondrion|
|Tissue Location||Expressed in lymphoid tissues (at protein level). Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung, lymphoid tissues and blood leukocytes.|
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DEAD box proteins, characterized by the conserved motifAsp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They areimplicated in a number of cellular processes involving alterationof RNA secondary structure such as translation initiation, nuclearand mitochondrial splicing, and ribosome and spliceosome assembly.Based on their distribution patterns, some members of this DEAD boxprotein family are believed to be involved in embryogenesis,spermatogenesis, and cellular growth and division. This geneencodes a member of this family. The function of this member hasnot been determined. Alternative splicing of this gene generates 2transcript variants, but the full length nature of one of thevariants has not been defined.
Huang, C., et al. J. Exp. Clin. Cancer Res. 28, 11 (2009) :Chen, Y., et al. Exp. Mol. Pathol. 82(3):256-261(2007)Alli, Z., et al. Anticancer Res. 27 (1A), 373-377 (2007) :Alli, Z., et al. Exp. Mol. Pathol. 81(3):245-248(2006)Alli, Z., et al. Cell. Immunol. 237(2):141-146(2005)
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