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PLXNC1 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O60486
Clone Names 100405233
Additional Information
Gene ID 10154
Other Names Plexin-C1, Virus-encoded semaphorin protein receptor, CD232, PLXNC1, VESPR
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13576b was selected from the C-term region of PLXNC1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLXNC1
Synonyms VESPR
Function Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Detected in heart, brain, lung, spleen and placenta.
Research Areas
Citations (0)
citation

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Background

PLXNC1 is a receptor for vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of viral semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity).

References

Liu, H., et al. Cell 142(5):749-761(2010)Lazova, R., et al. Am J Dermatopathol 31(2):177-181(2009)Scott, G.A., et al. J. Invest. Dermatol. 129(4):954-963(2009)Scott, G.A., et al. J. Invest. Dermatol. 128(1):151-161(2008)Li, Y., et al. PLoS ONE 3 (7), E2707 (2008) :

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$ 277.78
Cat# BP13576b
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Availability: 2 weeks
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