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TSPYL5 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q86VY4
Clone Names 91218262
Peptide ID 91218262
Additional Information
Gene ID 85453
Other Names Testis-specific Y-encoded-like protein 5, TSPY-like protein 5, TSPYL5, KIAA1750
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13583b was selected from the C-term region of TSPYL5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TSPYL5
Synonyms KIAA1750
Function Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.
Research Areas
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Background

The function of this protein remains unknown.

References

Kim, E.J., et al. Biochem. Biophys. Res. Commun. 392(3):448-453(2010)Jung, Y., et al. Lab. Invest. 88(2):153-160(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 80.00
Cat# BP13583b
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