|Other Names||Testis-specific Y-encoded-like protein 5, TSPY-like protein 5, TSPYL5, KIAA1750|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13583b was selected from the C-term region of TSPYL5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Kim, E.J., et al. Biochem. Biophys. Res. Commun. 392(3):448-453(2010)Jung, Y., et al. Lab. Invest. 88(2):153-160(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)
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