PCDH18 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9HCL0 |
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Clone Names | 100406072 |
Gene ID | 54510 |
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Other Names | Protocadherin-18, PCDH18, KIAA1562 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13587b was selected from the C-term region of PCDH18. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PCDH18 |
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Synonyms | KIAA1562 |
Function | Potential calcium-dependent cell-adhesion protein. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in all tissues, with highest expression in lung and ovary. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the protocadherin gene family, asubfamily of the cadherin superfamily. This gene encodes a proteinwhich contains 6 extracellular cadherin domains, a transmembranedomain and a cytoplasmic tail differing from those of the classicalcadherins. Although its specific function is undetermined, thecadherin-related neuronal receptor is thought to play a role in theestablishment and function of specific cell-cell connections in thebrain.
References
Homayouni, R., et al. Biochem. Biophys. Res. Commun. 289(2):539-547(2001)Wolverton, T., et al. Genomics 76 (1-3), 66-72 (2001) :Suzuki, S.T. Exp. Cell Res. 261(1):13-18(2000)Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000)Yagi, T., et al. Genes Dev. 14(10):1169-1180(2000)
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