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PCDH18 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9HCL0
Clone Names 100406072
Additional Information
Gene ID 54510
Other Names Protocadherin-18, PCDH18, KIAA1562
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13587b was selected from the C-term region of PCDH18. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PCDH18
Synonyms KIAA1562
Function Potential calcium-dependent cell-adhesion protein.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed in all tissues, with highest expression in lung and ovary.
Research Areas
Citations (0)
citation

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Background

This gene belongs to the protocadherin gene family, asubfamily of the cadherin superfamily. This gene encodes a proteinwhich contains 6 extracellular cadherin domains, a transmembranedomain and a cytoplasmic tail differing from those of the classicalcadherins. Although its specific function is undetermined, thecadherin-related neuronal receptor is thought to play a role in theestablishment and function of specific cell-cell connections in thebrain.

References

Homayouni, R., et al. Biochem. Biophys. Res. Commun. 289(2):539-547(2001)Wolverton, T., et al. Genomics 76 (1-3), 66-72 (2001) :Suzuki, S.T. Exp. Cell Res. 261(1):13-18(2000)Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000)Yagi, T., et al. Genes Dev. 14(10):1169-1180(2000)

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$ 277.78
Cat# BP13587b
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