|Other Names||Metal transporter CNNM4, Ancient conserved domain-containing protein 4, Cyclin-M4, CNNM4, ACDP4, KIAA1592|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13590b was selected from the C-term region of CNNM4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed. Highly expressed in heart.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the ancient conserved domaincontaining protein family. Members of this protein family contain acyclin box motif and have structural similarity to the cyclins. Theencoded protein may play a role in metal ion transport. Mutationsin this gene are associated with Jalili syndrome which consists ofcone-rod dystrophy and amelogenesis imperfecta. [provided byRefSeq].
Polok, B., et al. Am. J. Hum. Genet. 84(2):259-265(2009)Parry, D.A., et al. Am. J. Hum. Genet. 84(2):266-273(2009)Guo, D., et al. Mol Pain 1, 15 (2005) :Michaelides, M., et al. J. Med. Genet. 41(6):468-473(2004)Wang, C.Y., et al. Gene 306, 37-44 (2003) :
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