CNNM4 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6P4Q7 |
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Clone Names | 100406092 |
Gene ID | 26504 |
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Other Names | Metal transporter CNNM4, Ancient conserved domain-containing protein 4, Cyclin-M4, CNNM4, ACDP4, KIAA1592 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13590b was selected from the C-term region of CNNM4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CNNM4 |
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Synonyms | ACDP4, KIAA1592 |
Function | Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Widely expressed. Highly expressed in heart. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the ancient conserved domaincontaining protein family. Members of this protein family contain acyclin box motif and have structural similarity to the cyclins. Theencoded protein may play a role in metal ion transport. Mutationsin this gene are associated with Jalili syndrome which consists ofcone-rod dystrophy and amelogenesis imperfecta. [provided byRefSeq].
References
Polok, B., et al. Am. J. Hum. Genet. 84(2):259-265(2009)Parry, D.A., et al. Am. J. Hum. Genet. 84(2):266-273(2009)Guo, D., et al. Mol Pain 1, 15 (2005) :Michaelides, M., et al. J. Med. Genet. 41(6):468-473(2004)Wang, C.Y., et al. Gene 306, 37-44 (2003) :
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