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LIMS2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q7Z4I7 |
|---|---|
| Clone Names | 100406178 |
| Gene ID | 55679 |
|---|---|
| Other Names | LIM and senescent cell antigen-like-containing domain protein 2, LIM-like protein 2, Particularly interesting new Cys-His protein 2, PINCH-2, LIMS2, PINCH2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13597b was selected from the C-term region of LIMS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LIMS2 |
|---|---|
| Synonyms | PINCH2 |
| Function | Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration. |
| Cellular Location | Nucleus. Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
LIMS2 is a focal adhesion protein that associates withintegrin-linked kinase (ILK; MIM 602366), a multidomain proteinthat mediates multiple protein-protein interactions at adhesionsites between cells and the extracellular matrix (ECM).[supplied byOMIM].
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Kim, S.K., et al. Biochem. Biophys. Res. Commun. 349(3):1032-1040(2006)Zhang, Y., et al. J. Biol. Chem. 277(41):38328-38338(2002)Tu, Y., et al. J. Cell Biol. 153(3):585-598(2001)
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