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PODXL2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NZ53 |
|---|---|
| Clone Names | 100406221 |
| Gene ID | 50512 |
|---|---|
| Other Names | Podocalyxin-like protein 2, Endoglycan, PODXL2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13602b was selected from the C-term region of PODXL2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PODXL2 |
|---|---|
| Function | Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins. |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Endoglycan is a disulfide-linked homodimeric membrane protein belongong to the podocalyxin family.
References
Kerr, S.C., et al. J. Immunol. 181(2):1480-1490(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Fieger, C.B., et al. J. Biol. Chem. 278(30):27390-27398(2003)
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