|Other Names||Tripartite motif-containing protein 45, RING finger protein 99, TRIM45, RNF99|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13645b was selected from the C-term region of TRIM45. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May act as a transcriptional repressor in mitogen- activated protein kinase signaling pathway.|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Expressed in skeletal muscle, brain, heart and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the tripartite motif family.The encoded protein may function as a transcriptional repressor ofthe mitogen-activated protein kinase pathway. Alternatively splicedtranscript variants have been described.
Sardiello, M., et al. BMC Evol. Biol. 8, 225 (2008) :Wang, Y., et al. Biochem. Biophys. Res. Commun. 323(1):9-16(2004)
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