|Other Names||Membrane-associated phosphatidylinositol transfer protein 2, Phosphatidylinositol transfer protein, membrane-associated 2, PITPnm 2, Pyk2 N-terminal domain-interacting receptor 3, NIR-3, PITPNM2, KIAA1457, NIR3|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13660c was selected from the Center region of PITPNM2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions.|
|Cellular Location||Endomembrane system; Peripheral membrane protein|
|Tissue Location||Highly expressed in brain, heart, ovary, testis and thymus. Detected in small intestine, prostate, pancreas, skeletal muscle, liver, colon and placenta|
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Provided below are standard protocols that you may find useful for product applications.
PITPNM2 belongs to a family of membrane-associatedphosphatidylinositol transfer domain-containing proteins that sharehomology with the Drosophila retinal degeneration B (rdgB) protein(Ocaka et al., 2005 [PubMed 15627748]).
Ocaka, L., et al. Cytogenet. Genome Res. 108(4):293-302(2005)Tomsig, J.L., et al. J. Biol. Chem. 278(12):10048-10054(2003)Lev, S., et al. Mol. Cell. Biol. 19(3):2278-2288(1999)
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