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LRRN4 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8WUT4
Clone Names 100416095
Peptide ID 100416095
Additional Information
Other Names Leucine-rich repeat neuronal protein 4, Neuronal leucine-rich repeat protein 4, NLRR-4, LRRN4, C20orf75
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13663b was selected from the C-term region of LRRN4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LRRN4
Synonyms C20orf75
Function May play an important role in hippocampus-dependent long-lasting memory.
Cellular Location Membrane; Single-pass type I membrane protein EMBL; AK290123; BAF82812.1; -; mRNA EMBL; AL035461; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL118505; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; CH471133; EAX10397.1; -; Genomic_DNA EMBL; BC027720; AAH27720.1; -; mRNA CCDS; CCDS13097.1; - RefSeq; NP_689824.2; NM_152611.4 UniGene; Hs.149133; - UniGene; Hs.741648; - UniGene; Hs.741928; - ProteinModelPortal; Q8WUT4; - SMR; Q8WUT4; - BioGrid; 127893; 1 IntAct; Q8WUT4; 6 STRING; 9606.ENSP00000368135; - iPTMnet; Q8WUT4; - PhosphoSitePlus; Q8WUT4; - BioMuta; LRRN4; - DMDM; 90110015; - PaxDb; Q8WUT4; - PeptideAtlas; Q8WUT4; - PRIDE; Q8WUT4; - ProteomicsDB; 74707; - TopDownProteomics; Q8WUT4; - Ensembl; ENST00000378858; ENSP00000368135; ENSG00000125872 GeneID; 164312; - KEGG; hsa:164312; - UCSC; uc002wmo.4; human CTD; 164312; - DisGeNET; 164312; - EuPathDB; HostDB:ENSG00000125872.7; - GeneCards; LRRN4; - HGNC; HGNC:16208; LRRN4 HPA; HPA075974; - neXtProt; NX_Q8WUT4; - OpenTargets; ENSG00000125872; - PharmGKB; PA162394670; - eggNOG; KOG0619; Eukaryota eggNOG; COG4886; LUCA GeneTree; ENSGT00530000064159; - HOGENOM; HOG000231713; - HOVERGEN; HBG051176; - InParanoid; Q8WUT4; - OMA; GDIFKMT; - OrthoDB; EOG091G02GQ; - PhylomeDB; Q8WUT4; - TreeFam; TF351118; - ChiTaRS; LRRN4; human GenomeRNAi; 164312; - PRO; PR:Q8WUT4; - Proteomes; UP000005640; Chromosome 20 Bgee; ENSG00000125872; - CleanEx; HS_LRRN4; - Genevisible; Q8WUT4; HS GO; GO:0070062; C:extracellular exosome; HDA:UniProtKB GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central GO; GO:0007616; P:long-term memory; IBA:GO_Central GO; GO:0008542; P:visual learning; IEA:Ensembl CDD; cd00063; FN3; 1 Gene3D; 2.60.40.10; -; 1 Gene3D; 3.80.10.10; -; 2 InterPro; IPR003961; FN3_dom InterPro; IPR036116; FN3_sf InterPro; IPR013783; Ig-like_fold InterPro; IPR001611; Leu-rich_rpt InterPro; IPR003591; Leu-rich_rpt_typical-subtyp InterPro; IPR032675; LRR_dom_sf Pfam; PF00041; fn3; 1 Pfam; PF13855; LRR_8; 2 SMART; SM00060; FN3; 1 SMART; SM00369; LRR_TYP; 7 SUPFAM; SSF49265; SSF49265; 1 PROSITE; PS50853; FN3; 1 2: Evidence at transcript level; Complete proteome; Glycoprotein; Leucine-rich repeat; Membrane; Polymorphism; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix SIGNAL 1 18 CHAIN 19 740 Leucine-rich repeat neuronal protein 4 /FTId=PRO_0000021029 TOPO_DOM 19 679 Extracellular. TRANSMEM 680 700 Helical. TOPO_DOM 701 740 Cytoplasmic. REPEAT 51 74 LRR 1 REPEAT 75 97 LRR 2 REPEAT 98 123 LRR 3 REPEAT 125 144 LRR 4 REPEAT 145 168 LRR 5 REPEAT 174 197 LRR 6 REPEAT 203 226 LRR 7 REPEAT 228 251 LRR 8 REPEAT 253 276 LRR 9 REPEAT 277 300 LRR 10 DOMAIN 579 679 Fibronectin type-III {ECO:0000255|PROSITE-ProRule:PRU00316} COMPBIAS 529 532 Poly-Glu CARBOHYD 42 42 N-linked (GlcNAc...) asparagine CARBOHYD 176 176 N-linked (GlcNAc...) asparagine CARBOHYD 289 289 N-linked (GlcNAc...) asparagine CARBOHYD 379 379 N-linked (GlcNAc...) asparagine CARBOHYD 442 442 N-linked (GlcNAc...) asparagine CARBOHYD 622 622 N-linked (GlcNAc...) asparagine VARIANT 138 138 P -> L (in dbSNP:rs6107751) /FTId=VAR_025548 VARIANT 141 141 T -> A (in dbSNP:rs1884643) /FTId=VAR_051143 SEQUENCE 740 AA; 78843 MW; 3920447BB8665668 CRC64; MRQTLPLLLL TVLRPSWADP PQEKVPLFRV TQQGPWGSSG SNATDSPCEG LPAADATALT LANRNLERLP GCLPRTLRSL DASHNLLRAL STSELGHLEQ LQVLTLRHNR IAALRWGPGG PAGLHTLDLS YNQLAALPPC TGPALSSLRA LALAGNPLRA LQPRAFACFP ALQLLNLSCT ALGRGAQGGI AEAAFAGEDG APLVTLEVLD LSGTFLERVE SGWIRDLPKL TSLYLRKMPR LTTLEGDIFK MTPNLQQLDC QDSPALASVA THIFQDTPHL QVLLFQNCNL SSFPPWTLDS SQVLSINLFG NPLTCSCDLS WLLTDAKRTV LSRAADTMCA PAAGSSGPFS ASLSLSQLPG VCQSDQSTTL GASHPPCFNR STYAQGTTVA PSAAPATRPA GDQQSVSKAP NVGSRTIAAW PHSDAREGTA PSTTNSVAGH SNSSVFPRAA STTRTQHRGE HAPELVLEPD ISAASTPLAS KLLGPFPTSW DRSISSPQPG QRTHATPQAP NPSLSEGEIP VLLLDDYSEE EEGRKEEVGT PHQDVPCDYH PCKHLQTPCA ELQRRWRCRC PGLSGEDTIP DPPRLQGVTE TTDTSALVHW CAPNSVVHGY QIRYSAEGWA GNQSVVGVIY ATARQHPLYG LSPGTTYRVC VLAANRAGLS QPRSSGWRSP CAAFTTKPSF ALLLSGLCAA SGLLLASTVV LSACLCRRGQ TLGLQRCDTH LVAYKNPAFD DYPLGLQTVS
Research Areas
Citations (0)

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Background

LRRN4 may play an important role in hippocampus-dependent long-lasting memory (By similarity).

References

Stolk, L., et al. Nat. Genet. (2009) In press :Bando, T., et al. Mol. Cell. Biol. 25(10):4166-4175(2005)Deloukas, P., et al. Nature 414(6866):865-871(2001)

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$ 80.00
Cat# BP13663b
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