|Other Names||Vitamin K epoxide reductase complex subunit 1-like protein 1, VKORC1-like protein 1, VKORC1L1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13669a was selected from the N-term region of VKORC1L1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins.|
|Cellular Location||Endoplasmic reticulum membrane; Multi- pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Yin, T., et al. Thromb. Res. 122(2):179-184(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Rost, S., et al. Nature 427(6974):537-541(2004)
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