|Other Names||Protein phosphatase 1 regulatory subunit 3F, R3F, PPP1R3F|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13676b was selected from the C-term region of PPP1R3F. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Glycogen-targeting subunit for protein phosphatase 1 (PP1).|
|Cellular Location||Membrane; Single-pass membrane protein|
|Tissue Location||Expressed in brain, skeletal muscle and heart.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that has been identified asone of several type-1 protein phosphatase (PP1) regulatorysubunits. One or two of these subunits, together with thewell-conserved catalytic subunit, can form the PP1 holoenzyme,where the regulatory subunit functions to regulate substratespecificity and/or targeting to a particular cellular compartment.Alternative splicing results in multiple transcript variants.
Suttner, K., et al. J. Allergy Clin. Immunol. 125(6):1395-1399(2010)Piton, A., et al. Mol. Psychiatry (2010) In press :Ceulemans, H., et al. Bioessays 24(4):371-381(2002)Schindelhauer, D., et al. Genome Res. 6(11):1056-1069(1996)
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