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PTH Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P01270 |
|---|---|
| Clone Names | 100427022 |
| Gene ID | 5741 |
|---|---|
| Other Names | Parathyroid hormone, PTH, Parathormone, Parathyrin, PTH |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13695c was selected from the Center region of PTH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PTH |
|---|---|
| Function | PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells. |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a hormone secreted byparathyroid cells. This hormone elevates blood Ca2+ level bydissolving the salts in bone and preventing their renal excretion.Defects in this gene are a cause of familial isolatedhypoparathyroidism (FIH).
References
Giroux, S., et al. Bone 47(5):975-981(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Xu, M., et al. Bone 47(2):341-352(2010)Gardham, C., et al. Clin J Am Soc Nephrol 5(7):1261-1267(2010)Tawfeek, H., et al. PLoS ONE 5 (8), E12290 (2010) :
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