Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   HBG1 Antibody (Center) Blocking peptide   

HBG1 Antibody (Center) Blocking peptide

Synthetic peptide

     
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Primary Accession P69891
Clone Names 100427024
Peptide ID 100427024
Additional Information
Gene ID 3047
Other Names Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain, HBG1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13696c was selected from the Center region of HBG1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HBG1
Function Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
Tissue Location Red blood cells.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.

Background

The gamma globin genes (HBG1 and HBG2) are normallyexpressed in the fetal liver, spleen and bone marrow. Two gammachains together with two alpha chains constitute fetal hemoglobin(HbF) which is normally replaced by adult hemoglobin (HbA) atbirth. In some beta-thalassemias and related conditions, gammachain production continues into adulthood. The two types of gammachains differ at residue 136 where glycine is found in the G-gammaproduct (HBG2) and alanine is found in the A-gamma product (HBG1).The former is predominant at birth. The order of the genes in thebeta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta-- beta--3'.

References

Zhou, D., et al. Nat. Genet. 42(9):742-744(2010)Miccio, A., et al. Mol. Cell. Biol. 30(14):3460-3470(2010)Nuinoon, M., et al. Hum. Genet. (2009) In press :da Cunha, A.F., et al. Hemoglobin 33(6):439-447(2009)Hamid, M., et al. Hemoglobin 33(6):428-438(2009)

FeedBack
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abgent.com.

$ 80.00
Cat# BP13696c
Size:
Quantity:
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Crown-Flash18
Terms & Conditions