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Mouse Cdk3 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q80YP0
Clone Names 110316092
Additional Information
Other Names Cyclin-dependent kinase 3, Cell division protein kinase 3, Cdk3, Cdk3-ps, Cdkn3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13803b was selected from the C-term region of Mouse Cdk3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cdk3
Synonyms Cdk3-ps, Cdkn3
Function Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.
Research Areas
Citations (0)
citation

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Background

Probably involved in the control of the cell cycle. Interacts with a yet unknown type of cyclin. Can phosphorylate histone H1 (By similarity).

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$ 277.78
Cat# BP13803b
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