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AP1G2 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O75843
Clone Names 100318131
Peptide ID 100318131
Additional Information
Gene ID 8906
Other Names AP-1 complex subunit gamma-like 2, Gamma2-adaptin, G2ad, AP1G2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13809a was selected from the N-term region of AP1G2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AP1G2
Function May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV).
Cellular Location Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein Note=Mainly localized to perinuclear vesicular structures Colocalizes with HBV major surface antigen L and HBV core protein C in CD63-containing compartments. Colocalizes with HBV major surface antigen L to cis-Golgi-like structures
Tissue Location Expressed in all but one (skeletal muscle) tissues examined
Research Areas
Citations (0)

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Adaptins are important components of clathrin-coatedvesicles transporting ligand-receptor complexes from the plasmamembrane or from the trans-Golgi network to lysosomes. The adaptinfamily of proteins is compsed of four classes of molecules namedalpha, beta-, beta prime- and gamma- adaptins. Adaptins, togetherwith medium and small subunits, form a heterotetrameric complexcalled an adaptor, whose role is to promote the formation ofclathrin-coated pits and vesicles. The protein encoded by this geneis a gamma-adaptin protein and it belongs to the adaptor complexeslarge subunits family. This protein along with the complex isthought to function at some trafficking step in the complexpathways between the trans-Golgi network and the cell surface.There are two alternatively spliced transcript variants of thisgene encoding the same protein.


Doring, T., et al. Biochim. Biophys. Acta 1803(11):1252-1264(2010)Rost, M., et al. J. Biol. Chem. 283(46):32119-32130(2008)Lambert, C., et al. J. Virol. 81(17):9050-9060(2007)Lehner, B., et al. Genome Res. 14(7):1315-1323(2004)Mattera, R., et al. J. Biol. Chem. 279(9):8018-8028(2004)

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$ 80.00
Cat# BP13809a
Availability: In Stock
Bulk Size
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