Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   VPS4B Antibody (C-term) Blocking peptide   

VPS4B Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O75351
Clone Names 100318070
Peptide ID 100318070
Additional Information
Gene ID 9525
Other Names Vacuolar protein sorting-associated protein 4B, Cell migration-inducing gene 1 protein, Suppressor of K(+) transport growth defect 1, Protein SKD1, VPS4B, SKD1, VPS42
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13813b was selected from the C-term region of VPS4B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name VPS4B
Synonyms SKD1, VPS42
Function Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).
Cellular Location Prevacuolar compartment membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Note=Membrane-associated in the prevacuolar endosomal compartment. Localized in HIV-1 particles purified from acutely infected cells
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


The protein encoded by this gene is a member of the AAAprotein family (ATPases associated with diverse cellularactivities), and is the homolog of the yeast Vps4 protein. Inhumans, two paralogs of the yeast protein have been identified. Theformer share a high degree of aa sequence similarity with eachother, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1(suppressor of K+ transport defect 1) has been shown to be a yeastVps4 ortholog. Functional studies indicate that both human paralogsassociate with the endosomal compartments, and are involved inintracellular protein trafficking, similar to Vps4 protein inyeast. The gene encoding this paralog has been mapped to chromosome18; the gene for the other resides on chromosome 16. [provided byRefSeq].


Morita, E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(29):12889-12894(2010)McDonough, C.W., et al. Hum. Genet. (2009) In press :Bruce, E.A., et al. Virology 390(2):268-278(2009)Inoue, M., et al. Traffic 9(12):2180-2189(2008)Stuchell-Brereton, M.D., et al. Nature 449(7163):740-744(2007)

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 80.00
Cat# BP13813b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions