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DCBLD2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96PD2 |
|---|---|
| Clone Names | 100405117 |
| Gene ID | 131566 |
|---|---|
| Other Names | Discoidin, CUB and LCCL domain-containing protein 2, CUB, LCCL and coagulation factor V/VIII-homology domains protein 1, Endothelial and smooth muscle cell-derived neuropilin-like protein, DCBLD2, CLCP1, ESDN |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13827b was selected from the C-term region of DCBLD2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DCBLD2 |
|---|---|
| Synonyms | CLCP1, ESDN |
| Cellular Location | Membrane; Single- pass type I membrane protein |
| Tissue Location | Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
DCBLD2, otherwise known as ESDN (endothelial and smooth muscle cell-derived neuropilin-like molecule) is a novel type-I transmembrane protein with the longest cleavable secretory signal sequence among eukaryotes. It is expressed in various tissues; particularly highly expressed in cultured vascular smooth muscle cells. DCBLD2 is considered to play a role in regulation of vascular cell growth and may have a wide variety of functions in other tissues including the nervous system, like neuropilins.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :Guo, X., et al. J. Biol. Chem. 284(43):29376-29382(2009)Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)Kim, M., et al. Mol. Cancer Res. 6(2):222-230(2008)Sadeghi, M.M., et al. Am. J. Transplant. 7(9):2098-2105(2007)
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