|Other Names||Sulfate anion transporter 1, SAT-1, Solute carrier family 26 member 1, SLC26A1, SAT1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13831a was selected from the N-term region of SLC26A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate. Mediates sulfate and oxalate transport.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Expressed most abundantly in the kidney and liver, with lower levels in the pancreas, testis, brain, small intestine, colon, and lung.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of a family of sulfate/aniontransporter genes. Family members are well conserved in theirgenomic (number and size of exons) and protein (aa length amongspecies) structures, but have markedly different tissue expressionpatterns. This gene is primarily expressed in the liver, pancreas,and brain. Three splice variants that encode different isoformshave been identified.
Katzir, Z., et al. Nephrol. Dial. Transplant. 23(4):1211-1215(2008)Gornati, R., et al. Mol. Cell. Biochem. 298 (1-2), 59-68 (2007) :Regeer, R.R., et al. DNA Cell Biol. 22(2):107-117(2003)Markovich, D. Physiol. Rev. 81(4):1499-1533(2001)Lohi, H., et al. Genomics 70(1):102-112(2000)
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