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SLC26A1 Antibody (N-term ) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H2B4 |
|---|---|
| Clone Names | 100416079 |
| Gene ID | 10861 |
|---|---|
| Other Names | Sulfate anion transporter 1, SAT-1, Solute carrier family 26 member 1, SLC26A1, SAT1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13831a was selected from the N-term region of SLC26A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SLC26A1 |
|---|---|
| Synonyms | SAT1 |
| Function | Sodium-independent sulfate anion transporter (PubMed:12713736, PubMed:27125215). Can transport other anions including bicarbonate, thiosulfate and oxalate by mediating sulfate- thiosulfate, sulfate-hydrogencarbonate and sulfate-oxalate anion exchange (PubMed:12713736, PubMed:27125215). Mediates oxalate- hydrogencarbonate anion exchange (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P58735}; Multi-pass membrane protein. Basolateral cell membrane {ECO:0000250|UniProtKB:P45380}; Multi-pass membrane protein |
| Tissue Location | Expressed most abundantly in the kidney and liver, with lower levels in the pancreas, testis, brain, small intestine, colon, and lung. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of a family of sulfate/aniontransporter genes. Family members are well conserved in theirgenomic (number and size of exons) and protein (aa length amongspecies) structures, but have markedly different tissue expressionpatterns. This gene is primarily expressed in the liver, pancreas,and brain. Three splice variants that encode different isoformshave been identified.
References
Katzir, Z., et al. Nephrol. Dial. Transplant. 23(4):1211-1215(2008)Gornati, R., et al. Mol. Cell. Biochem. 298 (1-2), 59-68 (2007) :Regeer, R.R., et al. DNA Cell Biol. 22(2):107-117(2003)Markovich, D. Physiol. Rev. 81(4):1499-1533(2001)Lohi, H., et al. Genomics 70(1):102-112(2000)
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