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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CEACAM3 Antibody (C-term) Blocking peptide   

CEACAM3 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P40198
Clone Names 100427315
Peptide ID 100427315
Additional Information
Gene ID 1084
Other Names Carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen CGM1, CD66d, CEACAM3, CD66D, CGM1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13855b was selected from the C-term region of CEACAM3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD66D, CGM1
Function Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney
Research Areas
Citations (0)

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This gene encodes a member of the family ofcarcinoembryonic antigen-related cell adhesion molecules (CEACAMs),which are used by several bacterial pathogens to bind and invadehost cells. The encoded transmembrane protein directs phagocytosisof several bacterial species that is dependent on the small GTPaseRac. It is thought to serve an important role in controllinghuman-specific pathogens by the innate immune system. Alternativelyspliced transcript variants have been described, but theirbiological validity has not been determined.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Tsavaris, N., et al. J Chemother 21(6):673-680(2009)Skubitz, K.M., et al. J Transl Med 6, 78 (2008) :Stern-Ginossar, N., et al. J. Immunol. 179(7):4424-4434(2007)Ali, C.W., et al. J Gastrointest Cancer 38 (2-4), 108-114 (2007) :

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$ 80.00
Cat# BP13855b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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