|Other Names||Endothelin-2, ET-2, Preproendothelin-2, PPET2, EDN2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13863b was selected from the C-term region of EDN2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Endothelins are endothelium-derived vasoconstrictor peptides.|
|Tissue Location||Expressed in lung, but not in placental stem villi vessels or cultured placental villi smooth muscle cells|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the endothelin proteinfamily of secretory vasoconstrictive peptides. The preproprotein isprocessed to a short mature form which functions as a ligand forthe endothelin receptors that initiate intracellular signalingevents. This gene product is involved in a wide range of biologicalprocesses, such as hypertension and ovulation. [provided byRefSeq].
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Darrah, R., et al. Physiol. Genomics 41(1):71-77(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :Wiesmann, F., et al. Breast Cancer Res. 11 (3), R34 (2009) :
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