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EDN2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P20800 |
|---|---|
| Clone Names | 100430104 |
| Gene ID | 1907 |
|---|---|
| Other Names | Endothelin-2, ET-2, Preproendothelin-2, PPET2, EDN2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13863b was selected from the C-term region of EDN2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | EDN2 |
|---|---|
| Function | Endothelins are endothelium-derived vasoconstrictor peptides. |
| Cellular Location | Secreted. |
| Tissue Location | Expressed in lung, but not in placental stem villi vessels or cultured placental villi smooth muscle cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the endothelin proteinfamily of secretory vasoconstrictive peptides. The preproprotein isprocessed to a short mature form which functions as a ligand forthe endothelin receptors that initiate intracellular signalingevents. This gene product is involved in a wide range of biologicalprocesses, such as hypertension and ovulation. [provided byRefSeq].
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Darrah, R., et al. Physiol. Genomics 41(1):71-77(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :Wiesmann, F., et al. Breast Cancer Res. 11 (3), R34 (2009) :
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