|Other Names||Mucolipin-3, MCOLN3|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13868b was selected from the C-term region of MCOLN3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Mucolipins constitute a family of cation channel proteinswith homologs in mouse, Drosophila, and C. elegans. Mutations inthe human MCOLN1 gene (MIM 605248) cause mucolipodosis IV (MIM262650).
Kim, H.J., et al. J. Biol. Chem. 285(22):16513-16520(2010)Curcio-Morelli, C., et al. J. Cell. Physiol. 222(2):328-335(2010)Kim, H.J., et al. Traffic 10(8):1157-1167(2009)Martina, J.A., et al. Traffic 10(8):1143-1156(2009)Grimm, C., et al. J. Biol. Chem. 284(20):13823-13831(2009)
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