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OCLN Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q16625
Clone Names 100430255
Peptide ID 100430255
Additional Information
Gene ID 100506658
Other Names Occludin, OCLN
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13901b was selected from the C-term region of OCLN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name OCLN
Function May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions.
Cellular Location Cell membrane; Multi- pass membrane protein. Cell junction, tight junction
Tissue Location Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis
Research Areas
Citations (0)

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Background

This gene encodes an integral membrane protein which islocated at tight junctions. This protein may be involved in theformation and maintenance of the tight junction. The possibilityof several alternatively spliced products has been suggested butthe full nature of these products has not been described. [providedby RefSeq].

References

Liu, S., et al. Virology 407(1):160-170(2010)Michta, M.L., et al. J. Virol. 84(22):11696-11708(2010)O'Driscoll, M.C., et al. Am. J. Hum. Genet. 87(3):354-364(2010)Van Itallie, C.M., et al. J. Cell. Sci. 123 (PT 16), 2844-2852 (2010) :Raikwar, N.S., et al. Am. J. Physiol. Renal Physiol. 299 (2), F436-F444 (2010) :

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$ 80.00
Cat# BP13901b
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