Mouse Map3k2 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q61083 |
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Clone Names | 110316230 |
Other Names | Mitogen-activated protein kinase kinase kinase 2, MAPK/ERK kinase kinase 2, MEK kinase 2, MEKK 2, Map3k2, Mekk2 |
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Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13917a was selected from the N-term region of Mouse Map3k2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Map3k2 |
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Synonyms | Mekk2 |
Function | Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. Plays a role in caveolae kiss-and-run dynamics (By similarity). |
Cellular Location | Cytoplasm. Nucleus. Note=Upon EGF stimulation, translocates into the nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. Plays a role in caveolae kiss-and-run dynamics (By similarity).
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