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Mouse Mknk1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O08605
Clone Names 110316271
Additional Information
Gene ID 17346
Other Names MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1, Mknk1, Mnk1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13921a was selected from the N-term region of Mouse Mknk1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mknk1
Synonyms Mnk1
Function May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine- containing mRNA cap.
Tissue Location Ubiquitously expressed in all tissues examined, with high levels in skeletal muscle.
Research Areas
Citations (0)
citation

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Background

Mknk1 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.

References

Ueda, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):13984-13990(2010)Furic, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14134-14139(2010)Joshi, S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(29):12097-12102(2009)Wang, X., et al. Mol. Cell. Biol. 27(21):7405-7413(2007)Chrestensen, C.A., et al. Genes Cells 12(10):1133-1140(2007)

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$ 277.78
Cat# BP13921a
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Availability: 2 weeks
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