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Mouse Nek8 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q91ZR4
Clone Names 110316294
Peptide ID 110316294
Additional Information
Gene ID 140859
Other Names Serine/threonine-protein kinase Nek8, Never in mitosis A-related kinase 8, NimA-related protein kinase 8, Nek8, Jck
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13927b was selected from the C-term region of Mouse Nek8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Nek8
Synonyms Jck
Function Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through targeting of proteins to the cilia. Plays a role in organogenesis and is involved in the regulation of the Hippo signaling pathway.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, cilium Note=Predominantly cytoplasmic. Localizes to the proximal region of the primary cilium and is not observed in dividing cells
Tissue Location Kidney, liver, and testis.
Research Areas
Citations (0)

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This gene encodes a NIMA-related kinase. Members of thisserine/threonine protein kinase family are structurally-related toNIMA (never in mitosis, gene A) which controls mitotic signaling inAspergillus nidulans.


Hellman, N.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(43):18499-18504(2010)Ahmadie, R., et al. J. Nutr. 140(8):1438-1444(2010)Natoli, T.A., et al. Nat. Med. 16(7):788-792(2010)Shiba, D., et al. Cytoskeleton (Hoboken) 67(2):112-119(2010)Sohara, E., et al. J. Am. Soc. Nephrol. 19(3):469-476(2008)

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$ 80.00
Cat# BP13927b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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