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DAO Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P14920
Clone Names 90429095
Peptide ID 90429095
Additional Information
Gene ID 1610
Other Names D-amino-acid oxidase, DAAO, DAMOX, DAO, DAO, DAMOX
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13941c was selected from the Center region of DAO. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DAO
Synonyms DAMOX
Function Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Cellular Location Peroxisome.
Research Areas
Citations (0)

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This gene encodes the peroxisomal enzyme D-amino acidoxidase. The enzyme is a flavoprotein which uses flavin adeninedinucleotide (FAD) as its prosthetic group. Its substrates includea wide variety of D-amino acids, but it is inactive on thenaturally occurring L-amino acids. Its biological function is notknown; it may act as a detoxifying agent which removes D-aminoacids that accumulate during aging. In mice, it degrades D-serine,a co-agonist of the NMDA receptor. This gene may play a role in thepathophysiology of schizophrenia.


Kim, B., et al. Psychiatry Res 179(2):121-125(2010)Caldinelli, L., et al. Protein Sci. 19(8):1500-1512(2010)Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)Ohnuma, T., et al. Schizophr. Res. 118 (1-3), 300-302 (2010) :Mitchell, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(16):7556-7561(2010)

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$ 80.00
Cat# BP13941c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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