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ENKUR Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8TC29 |
|---|---|
| Clone Names | 90625075 |
| Gene ID | 219670 |
|---|---|
| Other Names | Enkurin, ENKUR, C10orf63 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13942c was selected from the Center region of ENKUR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ENKUR (HGNC:28388) |
|---|---|
| Synonyms | C10orf63 |
| Function | Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel (By similarity). Microtubule inner protein (MIP) part of the dynein- decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189). |
| Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q6SP97}. Note=Sperm acrosomal crescent and flagellar principal piece. {ECO:0000250|UniProtKB:Q6SP97} |
| Tissue Location | Expressed in airway epithelial cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Enkurin interacts with transient receptor potentialcanonical (TRPC) cation channels (see TRPC1; MIM 602343) andfunctions as an adaptor protein, tethering signal transductionproteins to TRPC channels (Sutton et al., 2004 [PubMed15385169]).
References
Beech, D.J. Handb Exp Pharmacol 179, 109-123 (2007) :Sutton, K.A., et al. Dev. Biol. 274(2):426-435(2004)Deloukas, P., et al. Nature 429(6990):375-381(2004)
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