|Other Names||Enkurin, ENKUR, C10orf63|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13942c was selected from the Center region of C10orf63. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel.|
|Cellular Location||Cell projection, cilium, flagellum. Note=Sperm acrosomal crescent and flagellar principal piece|
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Provided below are standard protocols that you may find useful for product applications.
Enkurin interacts with transient receptor potentialcanonical (TRPC) cation channels (see TRPC1; MIM 602343) andfunctions as an adaptor protein, tethering signal transductionproteins to TRPC channels (Sutton et al., 2004 [PubMed15385169]).
Beech, D.J. Handb Exp Pharmacol 179, 109-123 (2007) :Sutton, K.A., et al. Dev. Biol. 274(2):426-435(2004)Deloukas, P., et al. Nature 429(6990):375-381(2004)
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