|Other Names||Vesicle transport through interaction with t-SNAREs homolog 1B, Vesicle transport v-SNARE protein Vti1-like 1, Vti1-rp1, VTI1B, VTI1, VTI1L, VTI1L1, VTI2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13952c was selected from the Center region of VTI1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||VTI1, VTI1L, VTI1L1, VTI2|
|Function||V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.|
|Cellular Location||Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane. Cytoplasmic granule|
|Tissue Location||Expressed in all tissues examined.|
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V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
Furuta, N., et al. Mol. Biol. Cell 21(6):1001-1010(2010)Bilan, F., et al. Exp. Cell Res. 314 (11-12), 2199-2211 (2008) :Hirst, J., et al. Mol. Biol. Cell 15(12):5593-5602(2004)Yan, Q., et al. J. Biol. Chem. 279(18):18270-18276(2004)Martinez-Arca, S., et al. Proc. Natl. Acad. Sci. U.S.A. 100(15):9011-9016(2003)
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