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PLSCR4 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NRQ2
Clone Names 100406224
Additional Information
Gene ID 57088
Other Names Phospholipid scramblase 4, PL scramblase 4, Ca(2+)-dependent phospholipid scramblase 4, Cell growth-inhibiting gene 43 protein, TRA1, PLSCR4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13974c was selected from the Center region of PLSCR4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLSCR4
Function May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Expressed in heart, brain, placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, uterus, small intestine and colon. Not detected in peripheral blood lymphocytes
Research Areas
Citations (0)
citation

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Background

PLSCR4 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Sahu, S.K., et al. Biochim. Biophys. Acta 1790(10):1274-1281(2009)Py, B., et al. PLoS ONE 4 (3), E5006 (2009) :Shibata, H., et al. J. Biol. Chem. 283(15):9623-9632(2008)Wiedmer, T., et al. Biochim. Biophys. Acta 1467(1):244-253(2000)

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$ 277.78
Cat# BP13974c
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Availability: 2 weeks
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