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LRRC8B Antibody (N-term ) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6P9F7
Clone Names 100416034
Peptide ID 100416034
Additional Information
Gene ID 23507
Other Names Volume-regulated anion channel subunit LRRC8B, Leucine-rich repeat-containing protein 8B, T-cell activation leucine repeat-rich protein, TA-LRRP, LRRC8B, KIAA0231
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13978a was selected from the N-term region of LRRC8B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0231
Function Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8B constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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The exact function of LRRC8B remains unknown.


Rose, J. Phd, et al. Mol. Med. (2010) In press :Kubota, K., et al. FEBS Lett. 564 (1-2), 147-152 (2004) :Robertson, N.G., et al. Genomics 23(1):42-50(1994)

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$ 80.00
Cat# BP13978a
(40 western blots)
Availability: In Stock
Bulk Size
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