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FCGR2B Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P31994
Clone Names 100427132
Peptide ID 100427132
Additional Information
Gene ID 2213
Other Names Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD32, FCGR2B, CD32, FCG2, IGFR2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13987b was selected from the C-term region of FCGR2B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD32, FCG2, IGFR2
Function Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Is the most broadly distributed Fc-gamma- receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells
Research Areas
Citations (0)

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The protein encoded by this gene is a low affinityreceptor for the Fc region of immunoglobulin gamma complexes. Theencoded protein is involved in the phagocytosis of immune complexesand in the regulation of antibody production by B-cells. Variationsin this gene may increase susceptibilty to systemic lupuserythematosus (SLE). Several transcript variants encoding differentisoforms have been found for this gene.


Prokopec, K.E., et al. Clin. Immunol. 137(3):322-329(2010)Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)Zhang, C.Y., et al. J. Biol. Chem. 285(44):34250-34258(2010)Niederer, H.A., et al. Hum. Mol. Genet. 19(16):3282-3294(2010)Guilabert, A., et al. J. Am. Acad. Dermatol. 63(1):161-163(2010)

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$ 80.00
Cat# BP13987b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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