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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   IL1R1 Antibody (C-term) Blocking peptide   

IL1R1 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P14778
Clone Names 100427245
Peptide ID 100427245
Additional Information
Gene ID 3554
Other Names Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a, Interleukin-1 receptor type 1, membrane form, mIL-1R1, mIL-1RI, Interleukin-1 receptor type 1, soluble form, sIL-1R1, sIL-1RI, IL1R1, IL1R, IL1RA, IL1RT1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13994b was selected from the C-term region of IL1R1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL1R1
Synonyms IL1R, IL1RA, IL1RT1
Function Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
Cellular Location Membrane; Single-pass type I membrane protein Cell membrane. Secreted
Research Areas
Citations (0)

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The protein encoded by this gene is a cytokine receptorthat belongs to the interleukin 1 receptor family. This protein isa receptor for interleukin alpha (IL1A), interleukin beta (IL1B),and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an importantmediator involved in many cytokine induced immune and inflammatoryresponses. This gene along with interleukin 1 receptor, type II(IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in aregion mapped to chromosome 2q12.


Fragoso, J.M., et al. Immunol. Lett. 133(2):106-111(2010)Franchim, C.S., et al. Hypertens Pregnancy (2010) In press :Melen, E., et al. J. Allergy Clin. Immunol. 126(3):631-637(2010)de Wit, E., et al. Mamm. Genome (2010) In press :Ryckman, K.K., et al. PLoS ONE 5 (8), E12273 (2010) :

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$ 80.00
Cat# BP13994b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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