|Other Names||Pulmonary surfactant-associated protein D, PSP-D, SP-D, Collectin-7, Lung surfactant protein D, SFTPD, COLEC7, PSPD, SFTP4|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13998b was selected from the C-term region of SFTPD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||COLEC7, PSPD, SFTP4|
|Function||Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.|
|Cellular Location||Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film|
|Tissue Location||Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes).|
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Provided below are standard protocols that you may find useful for product applications.
SFTPD contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Hartshorn, K.L., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (3), L384-L392 (2010) :de Wit, E., et al. Mamm. Genome (2010) In press :Paantjens, A.W., et al. Transplantation 90(3):340-342(2010)Barlo, N.P., et al. Sarcoidosis Vasc Diffuse Lung Dis 26(2):155-161(2009)
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