|Other Names||Glutaredoxin-1, Thioltransferase-1, TTase-1, GLRX, GRX|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14007c was selected from the Center region of GLRX. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.|
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Provided below are standard protocols that you may find useful for product applications.
GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Singleton, W.C., et al. J. Biol. Chem. 285(35):27111-27121(2010)Engstrom, K.S., et al. Mutat. Res. 683 (1-2), 98-105 (2010) :Johnson, M.P., et al. Hum. Genet. 126(5):655-666(2009)Lancel, S., et al. Circ. Res. 104(6):720-723(2009)Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)
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