|Other Names||Early endosome antigen 1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2, EEA1, ZFYVE2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14008c was selected from the Center region of EEA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.|
|Cellular Location||Cytoplasm. Early endosome membrane; Peripheral membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
EEA1 binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.
Mishra, A., et al. Proc. Natl. Acad. Sci. U.S.A. 107(24):10866-10871(2010)Selak, S., et al. Neuroscience 143(4):953-964(2006)Ahtiainen, L., et al. Exp. Cell Res. 312(9):1540-1553(2006)Cabezas, A., et al. Gene 371(1):34-41(2006)Araki, N., et al. Cell Struct. Funct. 31(2):145-157(2006)
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