|Other Names||Ornithine decarboxylase, ODC, ODC1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14027b was selected from the C-term region of ODC1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Key enzyme of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes the rate-limiting enzyme of thepolyamine biosynthesis pathway which catalyzes ornithine toputrescine. The activity level for the enzyme varies in response togrowth-promoting stimuli and exhibits a high turnover rate incomparison to other mammalian proteins. Originally localized toboth chromosomes 2 and 7, the gene encoding this enzyme has beendetermined to be located on 2p25, with a pseudogene located on7q31-qter.
Chaturvedi, R., et al. Gastroenterology 139(5):1686-1698(2010)Zell, J.A., et al. J. Natl. Cancer Inst. 102(19):1513-1516(2010)Geerts, D., et al. Int. J. Cancer 126(9):2012-2024(2010)Hughes, D., et al. Colorectal Dis (2010) In press :Grimminger, P.P., et al. Clin Lung Cancer 11(2):114-119(2010)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.