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HCLS1 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P14317
Clone Names 100430315
Peptide ID 100430315
Additional Information
Gene ID 3059
Other Names Hematopoietic lineage cell-specific protein, Hematopoietic cell-specific LYN substrate 1, LckBP1, p75, HCLS1, HS1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14038b was selected from the C-term region of HCLS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HCLS1
Synonyms HS1
Function Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Cellular Location Membrane; Peripheral membrane protein Cytoplasm. Mitochondrion
Tissue Location Expressed only in tissues and cells of hematopoietic origin
Research Areas
Citations (0)

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Background

Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.

References

Muzio, M., et al. Leukemia 21(9):2067-2070(2007)Lim, J., et al. Cell 125(4):801-814(2006)Hao, J.J., et al. J. Biol. Chem. 280(45):37988-37994(2005)Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)Brunati, A.M., et al. J. Biol. Chem. 280(22):21029-21035(2005)

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$ 80.00
Cat# BP14038b
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