|Other Names||Hematopoietic lineage cell-specific protein, Hematopoietic cell-specific LYN substrate 1, LckBP1, p75, HCLS1, HS1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14038b was selected from the C-term region of HCLS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.|
|Cellular Location||Membrane; Peripheral membrane protein Cytoplasm. Mitochondrion|
|Tissue Location||Expressed only in tissues and cells of hematopoietic origin|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Muzio, M., et al. Leukemia 21(9):2067-2070(2007)Lim, J., et al. Cell 125(4):801-814(2006)Hao, J.J., et al. J. Biol. Chem. 280(45):37988-37994(2005)Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)Brunati, A.M., et al. J. Biol. Chem. 280(22):21029-21035(2005)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.