|Other Names||Nardilysin, N-arginine dibasic convertase, NRD convertase, NRD-C, NRD1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14048c was selected from the Center region of NRD1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.|
|Tissue Location||Primarily in adult heart, skeletal muscle, and testis and at much lower levels in other tissues|
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Provided below are standard protocols that you may find useful for product applications.
NRD1 cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.
Korovkina, V.P., et al. Am. J. Physiol., Cell Physiol. 296 (3), C433-C440 (2009) :Hiraoka, Y., et al. Biochem. Biophys. Res. Commun. 370(1):154-158(2008)Bernstein, H.G., et al. Neuroscience 146(4):1513-1523(2007)Nishi, E., et al. J. Biol. Chem. 281(41):31164-31172(2006)Hospital, V., et al. Protein Pept. Lett. 11(5):501-508(2004)
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