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PPP1R10 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q96QC0
Clone Names 100507028
Peptide ID 100507028
Additional Information
Gene ID 5514
Other Names Serine/threonine-protein phosphatase 1 regulatory subunit 10, MHC class I region proline-rich protein CAT53, PP1-binding protein of 114 kDa, Phosphatase 1 nuclear targeting subunit, Protein FB19, p99, PPP1R10, CAT53, FB19, PNUTS
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14051c was selected from the Center region of PPP1R10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP1R10
Synonyms CAT53, FB19, PNUTS
Function Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00649, ECO:0000269|PubMed:9450550}. Note=Found in discrete nucleoplasmic bodies and within nucleoli. Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase (By similarity).
Tissue Location Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas
Research Areas
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This gene encodes a protein with similarity to a ratprotein that has an inhibitory effect on protein phosphatase-1(PP1). The rat protein localizes to the nucleus and colocalizeswith chromatin at distinct phases during mitosis. This gene lieswithin the major histocompatibility complex class I region onchromosome 6.


Lee, J.H., et al. J. Biol. Chem. 285(32):24466-24476(2010)De Leon, G., et al. Int. J. Oncol. 36(5):1269-1275(2010)Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :Correia, A.P., et al. Neurosci. Lett. 457(3):129-132(2009)Lee, S.J., et al. Exp. Mol. Med. 41(3):189-200(2009)

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$ 80.00
Cat# BP14051c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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