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NRTN Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q99748
Clone Names 100507037
Peptide ID 100507037
Additional Information
Gene ID 4902
Other Names Neurturin, NRTN
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14055c was selected from the Center region of NRTN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRTN
Function Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

Neurturin is a member of the TGF-beta subfamily, TRN. Thisgene signals through RET and a GPI-linked coreceptor, and promotessurvival of neuronal populations. A neurturin mutation has beendescribed in a family with Hirschsprung Disease. [provided byRefSeq].

References

Fernandez, R.M., et al. J. Pediatr. Surg. 43(11):2042-2047(2008)Adly, M.A., et al. J. Am. Acad. Dermatol. 58(2):238-250(2008)Yoong, L.F., et al. J. Neurosci. 27(21):5603-5614(2007)Yoong, L.F., et al. J. Neurochem. 98(4):1149-1158(2006)Vargas-Leal, V., et al. J. Immunol. 175(4):2301-2308(2005)

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$ 80.00
Cat# BP14055c
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