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GLRB Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P48167
Clone Names 110111041
Peptide ID 110111041
Additional Information
Gene ID 2743
Other Names Glycine receptor subunit beta, Glycine receptor 58 kDa subunit, GLRB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14080c was selected from the Center region of GLRB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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This gene encodes the beta subunit of the glycinereceptor, which is a pentamer composed of alpha and beta subunits.The receptor functions as a neurotransmitter-gated ion channel,which produces hyperpolarization via increased chloride conductancedue to the binding of glycine to the receptor. Mutations in thisgene cause startle disease, also known as hereditary hyperekplexiaor congenital stiff-person syndrome, a disease characterized bymuscular rigidity. Alternative splicing results in multipletranscript variants.


Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :Ziegler, E., et al. Naunyn Schmiedebergs Arch. Pharmacol. 380(4):277-291(2009)Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :Ahrens, J., et al. Pharmacology 83(4):217-222(2009)

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$ 80.00
Cat# BP14080c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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