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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   SPN/CD43 Antibody (Center) Blocking peptide   

SPN/CD43 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P16150
Clone Names 101229058
Peptide ID 101229058
Additional Information
Gene ID 6693
Other Names Leukosialin, Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, CD43, SPN, CD43
Target/Specificity The synthetic peptide sequence used to generate the antibody AP14085c was selected from the Center region of SPN/CD43. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPN
Synonyms CD43
Function One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas
Research Areas
Citations (0)

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Sialophorin (leukosialin) is a major sialoglycoprotein onthe surface of human T lymphocytes, monocytes, granulocytes, andsome B lymphocytes, which appears to be important for immunefunction and may be part of a physiologic ligand-receptor complexinvolved in T-cell activation.


Urano-Tashiro, Y., et al. Infect. Immun. 76(10):4686-4691(2008)Mambole, A., et al. J. Biol. Chem. 283(35):23627-23635(2008)Seethala, R.R., et al. Appl. Immunohistochem. Mol. Morphol. 16(2):165-172(2008)Khunkaewla, P., et al. Mol. Immunol. 45(6):1703-1711(2008)Rawal, A., et al. Arch. Pathol. Lab. Med. 131(11):1673-1678(2007)

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$ 80.00
Cat# BP14085c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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