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FARSB Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NSD9 |
|---|---|
| Clone Names | 80118106 |
| Gene ID | 10056 |
|---|---|
| Other Names | Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS, FARSB, FARSLB, FRSB |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP14090b was selected from the C-term region of FARSB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | FARSB |
|---|---|
| Synonyms | FARSLB, FRSB |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a highly conserved enzyme that belongsto the aminoacyl-tRNA synthetase class IIc subfamily. This enzymecomprises the regulatory beta subunits that form a tetramer withtwo catalytic alpha subunits. In the presence of ATP, this tetrameris responsible for attaching L-phenylalanine to the terminaladenosine of the appropriate tRNA. A pseudogene located onchromosome 10 has been identified.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Finarov, I., et al. Structure 18(3):343-353(2010)Yu, X.Y., et al. Bioorg. Med. Chem. Lett. 14(5):1339-1342(2004)Vasil'eva, I.A., et al. Biochemistry Mosc. 69(2):143-153(2004)Moor, N., et al. Biochemistry 42(36):10697-10708(2003)
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