|Other Names||Sodium-coupled neutral amino acid transporter 5, Solute carrier family 38 member 5, System N transporter 2, SLC38A5, JM24, SN2, SNAT5|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14098a was selected from the N-term region of SLC38A5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||JM24, SN2, SNAT5|
|Function||Functions as a sodium-dependent amino acid transporter which countertransport protons. Mediates the saturable, pH- sensitive, and electrogenic cotransport of several neutral amino acids including glycine, asparagine, alanine, serine, glutamine and histidine with sodium.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Predominantly expressed in stomach, brain, liver, lung and intestinal tract.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a system Nsodium-coupled amino acid transporter involved in the transfer ofglutamine, asparagine, histidine, serine, alanine, and glycine. Theencoded protein does not transport charged amino acids, iminoacids, or N-alkylated amino acids. This transporter is notinhibited by lithium.
Broer, S. Physiol. Rev. 88(1):249-286(2008)Froyen, G., et al. Hum. Genet. 121(5):539-547(2007)Nakanishi, T., et al. Biochem. Biophys. Res. Commun. 281(5):1343-1348(2001)
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