|Other Names||Mitochondrial import inner membrane translocase subunit Tim23, TIMM23, TIM23|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP14103b was selected from the C-term region of TIMM23. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)Guo, Y., et al. J. Biol. Chem. 279(23):24813-24825(2004)Yamamoto, H., et al. Cell 111(4):519-528(2002)Moro, F., et al. EMBO J. 18(13):3667-3675(1999)Bauer, M.F., et al. J. Mol. Biol. 289(1):69-82(1999)
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